Specifications & Physical Properties
Physical State: Liquid
Appearance: Colorless to pale yellow
Assay (Content): 45.00 – 55.00%

n-Butylphosphonic Anhydride (T4P), CAS 163755-62-2, is a condensation reagent and coupling reagent used in amide, ester and related reactions. Commercial grades are commonly supplied as solutions, including approximately 50% T4P in Ethyl Acetate or DMF. Availability is reviewed according to concentration, solvent, specification, quantity, destination and project requirements.
T4P can be evaluated for peptide coupling and other amide or ester bond-forming reactions. Mild conditions may help limit racemization for suitable substrates, while phosphonate by-products can be addressed during aqueous work-up. Conversion, stereochemistry and purification needs should be checked for each route.
For chemical reference data, see PubChem.
Physical State: Liquid
Appearance: Colorless to pale yellow
Assay (Content): 45.00 – 55.00%

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